Alternatives

Cdk alternatives for AI agents.

Compare similar skills by workflow fit, trust score, quality, GitHub adoption, maintenance, and install readiness.

Current skill

Cdk

The Chemistry Development Kit

85
Quality
86
Trust
585
Stars
#1

Jvarkit

Similarity 127Trust 80Strong 73

Java utilities for Bioinformatics

523 starsMay 7, 2026 pushgeo-scienceJavaBioinformatics
$ npx skills add lindenb/jvarkit
#2

TDC

Similarity 126Trust 87Strong 84

Therapeutics Commons (TDC): Multimodal Foundation for Therapeutic Science

1.3K starsJul 13, 2025 pushgeo-scienceJupyter NotebookBioinformatics
$ npx skills add mims-harvard/TDC
#3

ColabFold

Similarity 123Trust 93Excellent 100

Making Protein folding accessible to all!

2.8K starsJun 15, 2026 pushgeo-scienceJupyter NotebookBioinformatics
$ npx skills add sokrypton/ColabFold
#4

Minimap2

Similarity 122Trust 89Excellent 100

A versatile pairwise aligner for genomic and spliced nucleotide sequences

2.2K starsMay 19, 2026 pushgeo-scienceCBioinformatics
$ npx skills add lh3/minimap2
#5

Scikit Bio

Similarity 122Trust 95Excellent 100

scikit-bio: a community-driven Python library for bioinformatics, providing versatile data structures, algorithms and educational resources.

1.2K starsJun 8, 2026 pushgeo-sciencePythonBioinformatics
$ npx skills add scikit-bio/scikit-bio
#6

Bioconda Recipes

Similarity 122Trust 89Excellent 100

Conda recipes for the bioconda channel.

1.8K starsJun 16, 2026 pushgeo-scienceShellBioinformatics
$ npx skills add bioconda/bioconda-recipes
#7

Omicverse

Similarity 122Trust 94Excellent 100

A python library for multi omics included bulk, single cell and spatial RNA-seq analysis.

1.0K starsJun 14, 2026 pushgeo-sciencePythonBioinformatics
$ npx skills add omicverse/omicverse
#8

Biojava

Similarity 121Trust 87Strong 79

:book::microscope::coffee: BioJava is an open-source project dedicated to providing a Java library for processing biological data.

622 starsMay 5, 2026 pushgeo-scienceJavaBioinformatics
$ npx skills add biojava/biojava
#9

Foldseek

Similarity 121Trust 91Excellent 96

Foldseek enables fast and sensitive comparisons of large structure sets.

1.2K starsMay 13, 2026 pushgeo-scienceCBioinformatics
$ npx skills add steineggerlab/foldseek
#10

Adam

Similarity 120Trust 92Excellent 92

ADAM is a genomics analysis platform with specialized file formats built using Apache Avro, Apache Spark, and Apache Parquet. Apache 2 licensed.

1.1K starsMar 17, 2026 pushgeo-scienceScalaBioinformatics
$ npx skills add bigdatagenomics/adam
#11

Gatk

Similarity 120Trust 89Excellent 99

Official code repository for GATK versions 4 and up

2.0K starsJun 16, 2026 pushgeo-scienceJavaBioinformatics
$ npx skills add broadinstitute/gatk
#12

Scispacy

Similarity 119Trust 88Excellent 86

A full spaCy pipeline and models for scientific/biomedical documents.

2.0K starsDec 4, 2025 pushgeo-sciencePythonBioinformatics
$ npx skills add allenai/scispacy
#13

Biotite

Similarity 118Trust 86Excellent 87

A comprehensive library for computational molecular biology

958 starsJun 11, 2026 pushgeo-sciencePythonBioinformatics
$ npx skills add biotite-dev/biotite
#14

Pysam

Similarity 118Trust 86Excellent 87

Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.

895 starsJun 3, 2026 pushgeo-scienceCythonBioinformatics
$ npx skills add pysam-developers/pysam
#15

Wdl

Similarity 117Trust 86Excellent 87

Specification for the Workflow Description Language (WDL).

852 starsJun 15, 2026 pushgeo-scienceBioinformaticsClaude Code
$ npx skills add openwdl/wdl
#16

Plantcv

Similarity 117Trust 86Excellent 86

Plant phenotyping with image analysis

798 starsJun 15, 2026 pushgeo-sciencePythonBioinformatics
$ npx skills add danforthcenter/plantcv

How to choose

When should you switch?

Use an alternative when it has a clearer install path, higher trust score, fresher maintenance, or better platform fit for your current agent stack. Keep Cdk if it already passes your workflow test and repository review.

Next step

Compare top candidates side by side

Open the compare page, test the install commands in a sandbox, and check each repository before using a skill in production.