OpenAgentSkill Registry Manifest
Skill: Pysam
Slug: pysam-developers-pysam
Category: geo-science
Description: Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.

Agent fit:
- Decision: 98/100 Production-ready
- Primary fit: Workflow automation
- Role: Primary pick

Supply profile:
- Track: Coding and developer agents
- Scenario: GitHub automation
- Applicable agents: Claude Code, CLI, Codex, Cursor, Cython
- Maintenance: 15d since push
- Risk: Safe to try

Trust:
- Trust score: 86/100 Production candidate
- Audit: 89/100 Safe to try

Attribution:
- Status: Community indexed
- Source: GitHub star discovery
- Creator: pysam-developers
- Claim URL: https://www.openagentskill.com/skills/pysam-developers-pysam#claim-this-skill

Install:
npx skills add pysam-developers/pysam

URLs:
- Web: https://www.openagentskill.com/skills/pysam-developers-pysam
- API: https://www.openagentskill.com/api/agent/skills/pysam-developers-pysam
- Install API: https://www.openagentskill.com/api/skills/pysam-developers-pysam/install
- Repository: https://github.com/pysam-developers/pysam